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All posts created by welkin

| posted 16 Apr, 2018 17:09
Cluster AL has only one major tail protein. There are several phages in the database as of April 2018 that show two, and this is not correct.
Posted in: Cluster AL Annotation Tipsone major tail protein
| posted 16 Apr, 2018 17:06
Cluster AK has one endolysin, and it should be labeled as "lysin A".
Posted in: Cluster AK Annotation Tipslysin A
| posted 16 Apr, 2018 17:05
Cluster AK does not have a lysin B.
Posted in: Cluster AK Annotation Tipsno lysin B
| posted 16 Apr, 2018 16:58
We do not know where the slippery sequence for the frameshift is in this cluster.
Posted in: Cluster DT Annotation TipsTail assembly chaperones?
| posted 16 Apr, 2018 16:56
Cluster DS contains a phage that was not isolated and sequenced by the SEA-PHAGES program. Its finders chose a different bp1 than we did, and annotated the genome differently. We do not curate, update, or QC this genome.

This phages is:
GMA2
Posted in: Cluster DS Annotation Tipsnon SEA-PHAGES genomes
| posted 16 Apr, 2018 16:52
Cluster DQ contains a phage that was not isolated and sequenced by the SEA-PHAGES program. Its finders chose a different bp1 than we did, and annotated the genome differently. We do not curate, update, or QC this genome.

This phage is:
GMA6
Posted in: Cluster DQ Annotation Tipsnon SEA-PHAGES genomes
| posted 16 Apr, 2018 16:48
cluster DM contains a capsid fusion protein in which the capsid, capsid maturation protease, and scaffolding proteins are all fused together in one long gene.
Posted in: Cluster DM Annotation Tipscapsid fusion
| posted 16 Apr, 2018 16:47
Lysin A, which is a single multi-domain protein in many Actinobacteriophages, is split at the domain boundaries encoded by two adjacent genes in cluster DM. The functions should be reported as "lysin A, whatever the domain is" to indicate that each gene does not encode the full lysin A.
Lysin A is also inbetween the portal and capsid fusion which is an unusual place.
Posted in: Cluster DM Annotation Tipslysin A in two parts
| posted 16 Apr, 2018 16:45
Lysin A, which is a single multi-domain protein in many Actinobacteriophages, is split at the domain boundaries encoded by two adjacent genes in cluster DN. The functions should be reported as "lysin A, whatever the domain is" to indicate that each gene does not encode the full lysin A.
Posted in: Cluster DN Annotation Tipslysin A in two parts
| posted 16 Apr, 2018 16:44
Lysin A, which is a single multi-domain protein in many Actinobacteriophages, is split at the domain boundaries encoded by two adjacent genes in cluster DL. The functions should be reported as "lysin A, whatever the domain is" to indicate that each gene does not encode the full lysin A.
Posted in: Cluster DL Annotation Tipslysin A in two parts