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All posts created by welkin

| posted 24 Apr, 2018 14:22
BC phages have a single endolysin gene, this should be labeled "lysin A".
Posted in: Cluster BC Annotation Tipslysin A
| posted 24 Apr, 2018 14:20
Cluster BC phages have a gene that appears equivalent to capsid morphogenesis protein identified in the Cluster B phages when analyzed by HHPred. This gene should be labeled "capsid morphogenesis protein" for consistency.
Posted in: Cluster BC Annotation Tipshead assembly protein
| posted 24 Apr, 2018 14:05
Cluster BB contains some phages that were not isolated and sequenced by the SEA-PHAGES program. Their finders annotated the genomes differently. We are taking on the QC of these genomes but haven't reviewed the files yet.
These phages are:
phiC31, TG1, and phiBT1
Posted in: Cluster BB Annotation Tipsnon SEA-PHAGES genomes
| posted 24 Apr, 2018 13:57
Cluster BA contains some phages that were not isolated and sequenced by the SEA-PHAGES program. Their finders chose a different bp1 than we did, and annotated their genomes differently. We do not curate, update, or QC these genomes.

These phages are:
SPB78, Sros11, and VWB.
Posted in: Cluster BA Annotation Tipsnon SEA-PHAGES genomes
| posted 24 Apr, 2018 13:54
AV phages encode a single endolysin, it should be labeled "lysin A".
Posted in: Cluster AV Annotation Tipslysin A
| posted 24 Apr, 2018 13:53
AV phages are myoviridae, and so encode tail tube and tail sheath proteins.
Posted in: Cluster AV Annotation Tipstail sheath
| posted 24 Apr, 2018 13:50
AV phages encode a large tail protein called a tail spike that is the functional equivalent of a tail fiber. It is large enough to be visible in the TEM, and its structural domains are based on beta-prisms and helices, rather than alpha coiled coils. The most famous example is the tail spike of Salmonella phage P22.
Posted in: Cluster AV Annotation Tipstail spike
| posted 24 Apr, 2018 13:45
Cluster AS phages encode a tail protein called a "tail spike". Tail spike is equivalent in function to a tail fiber, however, is characterized by triple beta-prisms and beta-coils, resulting in a large structure visible in the TEM. Salmonella phage P22 is the most famous tailspike enabled phage.
Posted in: Cluster AS Annotation Tipstail spike
| posted 24 Apr, 2018 13:43
AS phages have two small terminase genes, one adjacent to the large subunit, the other in the right arm of teh genome.
Posted in: Cluster AS Annotation Tipstwo small terminase subunits
| posted 24 Apr, 2018 13:25
there is a single endolysin in cluster AT phages, it is found upstream of the capsid maturation protease and should be labeled "lysin A".
Posted in: Cluster AT Annotation Tipslysin A