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How many holins?
| Link to this post | posted 09 Aug, 2017 16:30 | |
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I am looking at cluster J phages and there are instances where two holins have been called. Allowed? The structure is LysA-holin-LysB-holin. |
| Link to this post | posted 10 Aug, 2017 14:37 | |
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David, Which phages have the second potential holins? The cluster J phages I've looked at have pham 5845 between the two lysins, which does not look like a holin via HHPred (attached) and does not seem to have a transmembrane region by TMHMM? Karen |
129Kb| Link to this post | posted 10 Aug, 2017 14:46 | |
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Karen, That is indeed the "holin" I am looking at in Dmpstrdiver. It does not really seem like one to me based on all the evidence we have but I was wondering if there was evidence I don't know about for why this has been called a holin. Best, Dave |