Link to this post | posted 02 Apr, 2018 15:22
esmiller	Hi Lee, It would appear you are on the right track…. a small (ca. 100 residues?), basic (?) protein that binds and bends DNA. It could facilitate integration, like IHF, or excision. Does it form a new pham with proteins from other phages? Proteins similar to IHF, FIS, H-NS, HU…. etc. Not seen a similar protein, that I recall, in Paenibacillus larvae phages that we've sequenced. Best, Eric

Link to this post | posted 03 Mar, 2017 14:27
esmiller	Hi Vassie, Normally we should have room for 8-10 students. We are a little late in announcing the program this first time around (award notice timing, etc.) so maybe 8 participants this summer. Thanks for asking and…. please help spread the word! Best, Eric

Link to this post | posted 02 Mar, 2017 15:08

esmiller

If you are an undergraduate science major who is interested in pursuing a career in STEM, there is an exciting new opportunity to develop your skills while studying the interface between microbes and bees. BeeMORE is a USDA-funded Research and Extension Experience for Undergraduates who are interested in significantly advancing their research skills both in the field and in the laboratory. Potential projects include: Disease ecology of native pollinators Discovering new yeasts from beehives for brewing beer Metagenomic surveys of bees and hives Elucidating the gut microbiome of honey bee queens Logistics Program runs from May 30th to August 3rd 2017 (9 weeks), and some accommodations for travel can be provided Students will receive a $500 stipend per week ($4,500 total for the summer) PLUS free room and board at our Wolf Village Apartments Successful applicants will be paired with faculty mentor programs to conduct their own research most amenable to their research interests and background Activities will include presentations, group field trips, extension meetings, and the NC State Summer Undergraduate Research Symposium Apply now! DEADLINE: March 25th, 2017 Apply online at: http://harvest.cals.ncsu.edu/beemore/apply/ Have more questions? Email us at: eric_miller@ncsu.edu or drtarpy@ncsu.edu Many thanks, Eric

Link to this post | posted 22 Jun, 2016 20:59
esmiller	Thanks Dan. I was wondering if there was evidence of "crossing the divide", or if there were enough isolates and sequence information to address the divergence, etc.

Link to this post | posted 22 Jun, 2016 18:26

esmiller

I suspect the experts at Pitt know this, or there is a useful paper out there…… While the majority of mycobacteriophages are syphoviruses (non-contractile, flexible tails) there are contractile tailed myoviruses (or Syphoviridae, Myoviridae, if you prefer that). - I am aware of the C cluster myoviruses. Are there more clusters of myoviridae among the mycobacteriophages? - Is there a myoviridae phage that aligns most closely with a syphoviridae cluster and is thus an "odd one out", primarily due to its tail structure? - Has anyone compared the tail proteins of the two morphotypes of mycobacterial phages? How about a comparison of the head-tail connectors? Portal proteins? Terminases? - Finally, is there a lysogen containing a C cluster phage and does it contain a classical prophage integration? All questions piqued by topics discussed at the recent (successful!) symposium that well may be answered somewhere! Eric

Link to this post | posted 24 May, 2016 15:25
esmiller	David's death is very sad news; it upsets me deeply. David loved science and people. I laughed so many times with him. I can't imagine how much he will be missed by family, friends and colleagues, to whom I extend my sincere sympathy.

Link to this post | posted 25 Sep, 2015 16:04
esmiller	For "copy and paste" in DNA Master, we have at times found that while the key stroke commands don't work, the edit menu functions do work. A trivial contribution that might help!