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cdshaffer posted in Whole phage starterator reports
fbaliraine posted in Phage DoRead Start at 52714 bp with 8 bp overlap vs start at 52718 with 4 bp overlap?
Debbie Jacobs-Sera posted in Phage DoRead Start at 52714 bp with 8 bp overlap vs start at 52718 with 4 bp overlap?
TerD, tellurium resistance protein
| Link to this post | posted 14 Jul, 2019 21:22 | |
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Hello, We would like to propose the addition of TerD or tellurium resistance protein, or the equivalent, to the approved function list. We believe pham 15777, which currently includes: Shows compelling evidence for the functional call. Examination of the protein sequence here: >Geostin gp71 MINLTKGSAPVTLSKAARMSVRITWPAATDYDAGAEILYKDGTTESIATFGARGVDAKLTSLTGKVRHNGDATRGAGTATETIDIDHDDEIVEIRPWAYSAQSNGTGSFRKYAVSMEVSNGTDTVKIDANNASNHDNVYTCVPAVLRFTGDGVQVEYAELYSDPRSEARPAFKKSGLLGKLKFTMDGPRNNYK By HHPred: https://toolkit.tuebingen.mpg.de/#/jobs/SEAGEOSTIN71 And by BlastP: https://blast.ncbi.nlm.nih.gov/Blast.cgi?CMD=Get&RID=JPXJD11B01R Shows high coverage and high confidence matches to the tellurium resistance protein TerD in multiple bacterial species. A brief literature search found that the gene has been found in phages infecting : Salmonella and Cronobacter spp.: https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-14-481 and https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7414, Pseudomona spp https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178739/, Clostridium spp. https://www.ncbi.nlm.nih.gov/pubmed/17322187, and Bacillus spp.: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178739/ The domain, as shown in Phamerator is also found by the CDD: https://www.ncbi.nlm.nih.gov/Structure/cdd/wrpsb.cgi?RID=JPXJCJHM01R Thanks, Steve |
| Link to this post | posted 15 Jul, 2019 14:53 | |
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Hi Steve, We think "tellurium resistance protein D family" is the way to go. "Ter" is also the TLA for the terminase genes (which we also don't use) and we may sow confusion if we don't spell things out. Thanks! |
| Link to this post | posted 15 Jul, 2019 17:07 | |
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Excellent, thanks! Steve |
| Link to this post | posted 29 Jul, 2019 16:44 | |
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Hi Welkin, Just double-checking before submission. If we are naming the protein product, shouldn't it be "tellurium resistance D family protein", rather than "tellurium resistance protein D family"? Ivan |
| Link to this post | posted 03 Aug, 2019 21:15 | |
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Welkin, Should we use D family protein or protein D family? I think that's all we need, then can submit. Thanks! Steve |