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one protein with DNA binding and membrane domains
| Link to this post | posted 02 Jun, 2018 10:45 | |
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Hi All, I found a gene product in cluster K1 genome of Mynx that encodes both a DNA binding domain and four transmembrane (MB) domains. See attached evidence. The four MB domains run from residues 13 - 136 and the DNA binding domain is on the very C-terminus (residues 244 - 280ish). Can I call both of these domains on one protein? Thanks! Sally |
390Kb| Link to this post | posted 02 Jun, 2018 10:47 | |
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I just found the answer on the function list. Going with most specific function of HTH DNA binding domain |
| Link to this post | posted 02 Jun, 2018 15:20 | |
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Sally, Hi. What gene are your questions about? The two functions together a DNA binding protein that sticks to the host membrane is more interesting than either a DNA binding protein or a membrane protein. I would call it as you have decided for now, but just curious. debbie |