SEA-PHAGES | Functions not on the approved list

Functions not on the approved list

Link to this post \| posted 15 Feb, 2022 16:06
NWCiowaSEAPHAGE	lhughes Another one from Abt2graduatex2: RNase adapter protein RapZ The genome has this function (not on the approved list) for gp55. I compared the HHPRED data for the equivalent gene in BabyGotBac (gp56, which was annotated as "ATPase" and found there is 100% probability, 90% coverage, and E-value of 0 to the RNase adapter protein (RapZ in E.coli). The function in Uniprot is given as "Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ" Thoughts on this function? Lee Hi! I'm looking to see if Lee got an answer on this one and can't find it. We have phage Santhid (cluster DY) gp56 with a similar hit on HHPred. 100% probability 86% coverage e = 1x10-32. The hit is to a RNAse adapter protein RapZ. What was your final call and why, Lee? Thanks, Sara

Link to this post | posted 15 Feb, 2022 16:06

lhughes
Another one from Abt2graduatex2: RNase adapter protein RapZ

The genome has this function (not on the approved list) for gp55. I compared the HHPRED data for the equivalent gene in BabyGotBac (gp56, which was annotated as "ATPase" and found there is 100% probability, 90% coverage, and E-value of 0 to the RNase adapter protein (RapZ in E.coli).

The function in Uniprot is given as "Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ"

Thoughts on this function?

Lee

Hi! I'm looking to see if Lee got an answer on this one and can't find it. We have phage Santhid (cluster DY) gp56 with a similar hit on HHPred. 100% probability 86% coverage e = 1x10-32. The hit is to a RNAse adapter protein RapZ. What was your final call and why, Lee?
Thanks, Sara

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Functions not on the approved list