Welcome to the forums at seaphages.org. Please feel free to ask any questions related to the SEA-PHAGES program. Any logged-in user may post new topics and reply to existing topics. If you'd like to see a new forum created, please contact us using our form or email us at info@seaphages.org.
Recent Activity
DNA binding protein, HU-like
| Link to this post | posted 17 Apr, 2018 18:40 | |
|---|---|
|
I am looking at Cluster BH phages and have found a product that doesn't seem to fit the existing types of DNA binding proteins already on the official list. The HHPRED results for Crosby_9225-8866 gene product are attached. Hits are at 99% probability and e-values of 10^-21 and coverage over most of the query. There are a number of hits called DNA-binding HU or Histone-like. A paper that talks about a possible role of one of these hits in DNA bending is http://emboj.embopress.org/content/22/14/3749 . On PECAAN, the Conserved Domain hits are also to this HU-like domain. Currently, all the members of the Pham are found in Cluster BH phages only. I suggest that we add a new type of DNA binding function "DNA binding protein, HU-like" Lee |
83Kb| Link to this post | posted 17 Apr, 2018 18:49 | |
|---|---|
|
sounds good to me. make it HU-like domain though. Crosby is for Sidney, no? |
| Link to this post | posted 17 Apr, 2018 20:09 | |
|---|---|
|
|
Welkin Pope Wasn't sure what you were asking until I googled it  Thanks on the name edit to "DNA binding, HU-like domain" |
| Link to this post | posted 18 Apr, 2018 14:36 | |
|---|---|
|
|
Lee HughesI just can't even…. You are sentenced to watch play-off hockey for at least another week.Welkin Pope |