Dr. Bono's research focuses on evolution in a changing environment.Understanding the fantastic biodiversity that is seen in the world requires both an understanding of the mechanisms generating such diversity and the selective forces that favor it. Although the interplay between ecology and evolution was historically separated by time scales, the complex dynamics between these forces have recently become better recognized; arguably nowhere more so than in viruses. Dr. Bono's research program focuses on these issues using viruses as both a model system to study general questions in biology but also the ecology and evolution of viruses themselves. Much of her research utilizes an experimental evolution approach with bacteria-infecting viruses (bacteriophages or simply phages), such as the Pseudomonas syringae phage phi6, but also includes influenza and environmental isolated phage.