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Recent Activity

spanins

Link to this post \| posted 23 May, 2024 18:53
stpage	Has anyone done a deep dive on phage spanins? Is it worth looking at or would we need some wetlab support anyway? Shallee

Link to this post \| posted 23 May, 2024 20:28
debbie	Hi Shallee, Rick Pollenz is looking at transmembrane proteins associated with the lysin genes. He may have more insight. Though I am not an expert, it is my understanding that our lysin Bs 'contain' the analogous spanin function of the enteric bacteriophages. So we have avoided using 'spanin' in lieu of lysin B. with the difference in cell walls we would want to be careful that are calls do not cause confusion. You are welcome to deep dive this topic! debbie Edited 23 May, 2024 20:29

Link to this post | posted 23 May, 2024 20:28

debbie

Hi Shallee,
Rick Pollenz is looking at transmembrane proteins associated with the lysin genes. He may have more insight.
Though I am not an expert, it is my understanding that our lysin Bs 'contain' the analogous spanin function of the enteric bacteriophages. So we have avoided using 'spanin' in lieu of lysin B. with the difference in cell walls we would want to be careful that are calls do not cause confusion. You are welcome to deep dive this topic!
debbie

Edited 23 May, 2024 20:29

Link to this post \| posted 28 May, 2024 12:03
stpage	Ok, thanks.