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Debbie Jacobs-Sera posted in Validating Translational Frameshifts in DNA Master
Lee Hughes posted in Validating Translational Frameshifts in DNA Master
storksle posted in Validating Translational Frameshifts in DNA Master
storksle posted in Validating Translational Frameshifts in DNA Master
storksle posted in Validating Translational Frameshifts in DNA Master
ribosomal protein l7/l12
| Link to this post | posted 04 Jun, 2023 21:35 | |
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I am looking at Stop-8213 in Enygma, a BE cluster phage. HHPred finds significant homology to L7/L12 subunit proteins of the 50S Ribosome in two bacterial species. There is however no detected sequence homology to back this up. Homology occurs across a significant chunk of the Pham, but not its entirety. aa sequence–MERIEIVQQVGNYFPDTKIADALRFAGDIDRGFARKMEDAQYKAEDEKYEYAEKRYNEGVKAGKESVRTTFDPQVVEATIWATTNFTDRDLTRKITCIKVLRDKFRPLGLIEAKTIMDMIKPLGTTDTLDWPKIVEAEKDSPELATQSALNALRNKLTNNEVARESIDSEESESNDYSTCPCGCGGMA https://www.rcsb.org/structure/1DD3 I suspect that we need more evidence, but thought it worthwhile enough to post. |
| Link to this post | posted 06 Jun, 2023 01:20 | |
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I agree it is not enough yet. but good to make the post. debbie |