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Potential minor capsid protein

| posted 22 Jul, 2021 22:34
I'm going over the annotation for phage SBlackberry (cluster EJ) and I'm trying to determine the right call for gene 14. Gene 14 is part of Pham 53136 and in cluster CZ it has been annotated as a minor capsid protein whereas in cluster EJ it has been annotated as NKF. According to HHPRED there's a match to a minor capsid protein (99.4% probability, 83% coverage, 3.1e-12 e-value). Based on this info I'm leaning towards calling it a minor capsid protein but any advice is appreciated.
| posted 28 Jul, 2021 01:22
Hi Arturo,
Sorry for the delay on this one. One of the hits is with HK97_gp10. This phage was well studied in the Hendrix lab here at Pitt, and they are have studied capsid proteins in depth. They could not determine what its function was, so I would not call it a minor capsid protein, and stick with Hypothetical Protein for now.
| posted 17 Nov, 2021 00:04
Thank you for the question Arturo and the answer Debbie - we had the same question for our Cluster DE phage ObLaDi. Much appreciated!
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