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host-nuclease inhibitor protein, Gam like
Link to this post | posted 11 Aug, 2018 00:22 | |
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The product of gene 37 (28052,28756) in Darolasnstone has a couple of nice HHPred matches (95-96% probability, 61% coverage, E value of 0.027) to the Bacteriophage Mu Gam protein. "This family consists of bacterial and phage Gam proteins. The gam gene of bacteriophage Mu encodes a protein which protects linear double stranded DNA from exonuclease degradation in vitro and in vivo" http://pfam.xfam.org/family/PF07352.11 https://www.rcsb.org/structure/2P2U There is a nice paper suggesting homology between Gam and Ku (which is on approved list) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1315809/ I'd like to suggest we add Gam-like host-nuclease inhibitor protein to the function list |