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Recent Activity
Debbie Jacobs-Sera posted in Help with Annotating Direct Terminal Repeats
Marie Fogarty posted in Help with Annotating Direct Terminal Repeats
cdshaffer posted in Help with Annotating Direct Terminal Repeats
Marie Fogarty posted in Help with Annotating Direct Terminal Repeats
Debbie Jacobs-Sera posted in Potential minor tail proteins in cluster GK
Lysin B
| Link to this post | posted 19 May, 2017 16:32 | |
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Can't find lysin B? No worries! Cluster B2 phages do not have a lysin B! |
| Link to this post | posted 17 Aug, 2017 01:44 | |
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A bunch of genes in pham 609, such as Eremos_49 and other Cluster B1 phages are labeled as Lysin B. HHPred seems to support this with hits to Cutinase. However, what I cannot find is Holin! The genes called as lysin B do have 3 transmembrane domains, so I am very confused! |
| Link to this post | posted 17 Aug, 2017 02:53 | |
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Cluster B2s lack lysin B. I thought there was pretty good evidence of pham 609 being annotated as lysin B based on HHPred and TMM data. In this 2016 paper (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912749/) they have Numberten and Pops (both B1s) containing both lysin A and lysin B. |
| Link to this post | posted 17 Aug, 2017 14:31 | |
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Cluster B1s definitely have lysinB calls. As far as I can tell the Holin has not been identified in B1s. It most assuredly has one but it is not clear which gene it is. |
| Link to this post | posted 20 Aug, 2018 15:57 | |
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Thanks guys– I left the "2" out of the starting post. You are all correct: B1s do have lysin B. |