Welcome to the forums at seaphages.org. Please feel free to ask any questions related to the SEA-PHAGES program. Any logged-in user may post new topics and reply to existing topics. If you'd like to see a new forum created, please contact us using our form or email us at info@seaphages.org.
Recent Activity
Lysogeny in cluster K1 mycobacteriophages
| Link to this post | posted 03 Aug, 2021 17:07 | |
|---|---|
|
Hi, The cluster K1 mycobacteriophage that we annotated with our students this past semester, Stinson, contains an immunity repressor (gene 44). As immunity repressor genes can down-regulate lytic gene expression, we were wondering whether Stinson-like phages might be able to lysogenize their hosts and whether any might have been found as prophages? Best, Susanne |
| Link to this post | posted 04 Aug, 2021 21:46 | |
|---|---|
|
It does not look like any of the cluster K1 phage in the sea phages database were found as prophages but the all of them are classified as temperate and the early phage for the cluster could make lysogens. See: Pope et al "Cluster K mycobacteriophages: insights into the evolutionary origins of mycobacteriophage TM4" |
| Link to this post | posted 04 Aug, 2021 22:19 | |
|---|---|
|
|
Thank you! |