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Clicking Supporting Evidence in PECAAN
Link to this post | posted 31 Aug, 2020 19:16 | |
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Hello, I'm wondering if when using PECAAN we are only supposed to click on the evidence if it supports our function? For one of our NKF genes, HHPRED is giving us a DNA-binding domain with 38% coverage. I know that this is not good evidence for a function for our gene but it is evidence that we are going to call it NKF - so the question is do we check the box? NCBI blast has 100% identity and aligned with hypothetical protein so we would definitely check that box. The conserved domain database shows nothing and the Transmembrane prediction shows that it's not a transmembrane protein. Do we click the use as evidence box to show that we looked at it and we think that its is not a transmembrane protein? I hope that the question makes sense. Thanks, Sarah |