SEA-PHAGES Logo

The official website of the HHMI Science Education Alliance-Phage Hunters Advancing Genomics and Evolutionary Science program.

Welcome to the forums at seaphages.org. Please feel free to ask any questions related to the SEA-PHAGES program. Any logged-in user may post new topics and reply to existing topics. If you'd like to see a new forum created, please contact us using our form or email us at info@seaphages.org.

ribosomal protein l7/l12

| posted 04 Jun, 2023 21:35
I am looking at Stop-8213 in Enygma, a BE cluster phage. HHPred finds significant homology to L7/L12 subunit proteins of the 50S Ribosome in two bacterial species. There is however no detected sequence homology to back this up. Homology occurs across a significant chunk of the Pham, but not its entirety.

aa sequence–MERIEIVQQVGNYFPDTKIADALRFAGDIDRGFARKMEDAQYKAEDEKYEYAEKRYNEGVKAGKESVRTTFDPQVVEATIWATTNFTDRDLTRKITCIKVLRDKFRPLGLIEAKTIMDMIKPLGTTDTLDWPKIVEAEKDSPELATQSALNALRNKLTNNEVARESIDSEESESNDYSTCPCGCGGMA

https://www.rcsb.org/structure/1DD3

I suspect that we need more evidence, but thought it worthwhile enough to post.
| posted 06 Jun, 2023 01:20
I agree it is not enough yet. but good to make the post.
debbie
 
Login to post a reply.