Welcome to the forums at seaphages.org. Please feel free to ask any questions related to the SEA-PHAGES program. Any logged-in user may post new topics and reply to existing topics. If you'd like to see a new forum created, please contact us using our form or email us at info@seaphages.org.
Recent Activity
SSB protein or RecT-like pairing protein
| Link to this post | posted 03 Apr, 2023 12:48 | |
|---|---|
|
We are looking at a gene in Culver (CQ1) with stop codon 56145, and debating what to call its official function. In HHPred, it has several matches to DNA binding protein. In BLAST, top hits are listed as RecT-like ssDNA annealing protein or RecT-like ssDNA binding protein. This gene does appear to be downstream from a putative RecE-like exonuclease. RecT-like ssDNA binding protein is no longer on the official function list and it looks like the naming of ssDNA binding protein is changing. Based on the official functions, we are uncertain if we should just call this the generic “SSB protein”, or “RecT-like pairing protein”. Thank you! |
| Link to this post | posted 03 Apr, 2023 12:54 | |
|---|---|
|
Hi Ellen, If you hit a single stranded DNA binding protein downstream of a RecE, it is likely that you have its companion protein, RecT-like DNA pairing protein and I would call it. To learn more about RecE and RecT, reading this paper may help. https://pubmed.ncbi.nlm.nih.gov/18923412/ |