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AV gene overlap

Link to this post \| posted 05 Apr, 2021 21:44
Tamarah_Adair	We are curious about the overlapping genes called in the AV cluster, such as Nellie 29/30 and Jasmine 32/33. Is there any information on this type of overlap being found in other phages or something else I am missing out on here? Thanks.

Link to this post \| posted 06 Apr, 2021 00:26
debbie	Hi Tammy, It is not a common occurrence, for sure. In this case (and I used Nellie), the coding potential for gene 30 is best, so I want to call that one for sure. However, the HHPred for 29 is compelling (I would call it a WhiB, I think.) so I really want to call it. Because their direction has them running into each other, there is really no reason that they couldn't both be transcribed. debbie Edited 06 Apr, 2021 00:29

Link to this post | posted 06 Apr, 2021 00:26

debbie

Hi Tammy,
It is not a common occurrence, for sure.
In this case (and I used Nellie), the coding potential for gene 30 is best, so I want to call that one for sure. However, the HHPred for 29 is compelling (I would call it a WhiB, I think.) so I really want to call it. Because their direction has them running into each other, there is really no reason that they couldn't both be transcribed.
debbie

Edited 06 Apr, 2021 00:29

Link to this post \| posted 07 Apr, 2021 19:46
Tamarah_Adair	OK. Thanks.

Link to this post \| posted 07 Apr, 2021 19:46
Tamarah_Adair	OK. Thanks.