SEA-PHAGES Logo

The official website of the HHMI Science Education Alliance-Phage Hunters Advancing Genomics and Evolutionary Science program.

Welcome to the forums at seaphages.org. Please feel free to ask any questions related to the SEA-PHAGES program. Any logged-in user may post new topics and reply to existing topics. If you'd like to see a new forum created, please contact us using our form or email us at info@seaphages.org.

Terminase, small subunit in right arm

| posted 04 Jun, 2023 19:53
The terminase small subunit is in the right-hand arm of the genome. Example is gene 57 in TaylorSipht (cluster AS1). This gene has a strong hit to PDB 6Z6E_C, with 99.79 probability, 3.8e-18, and 100 columns aligned out of 160. Alignment is to the helix-turn-helix-turn-helix structure of "Terminase small subunit; genome packaging, bacteriophage, DNA binding, VIRAL PROTEIN; 1.4A {Enterobacteria phage HK97}".
Do not call two small terminases, nor assign terminase small subunit function to the early gene (example, gene 2 in TaylorSipht).
Edited 19 Jul, 2023 19:49
| posted today, 15:41
for more discussion on this matter see this discussion:
https://seaphages.org/forums/topic/5775/
 
Login to post a reply.