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SAM lyase ?
Link to this post | posted yesterday, 19:34 | |
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There are several putative SAM-degrading enzymes in HollowPurple (e.g., SAM lyase –gp#120 w/ stop codon at 62,755 – evidence is based on HHpred hits; see the entry in PECAAN). If real, these are probably a counter-defense against the bacterial restriction-modification system. (see https://doi.org/10.7554/eLife.61818). There are no SAM-degrading enzymes in other phages in seaphages.org. Thoughts on including this? |
Link to this post | posted today, 08:51 | |
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mthomas Can you post the HHPRED coverage and percent identity? What do you get when you do an amino acid sequence alignment against the SAM lyase from T3? |