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This abstract was last modified on March 4, 2022 at 7:43 a.m..

Arizona State University
Corresponding Faculty Member: Susanne Pfeifer, spfeife1@asu.edu
This abstract will NOT be considered for a talk.
What’s in a gene? The annotated genome of the Mycobacteriophage Phegasus
Gabriella Cerna, Tyler Johnston, Shriya Kakde, Keith Karuku, Maria Kowal, Jasmine Monahan, Jillian Murray, Teresa Nguyen, Aurely Sanchez Carreon, Abigail Streiff, Blake Su, Faith Youkhana, Saige Munig, Zeel Patel, Cyril J Versoza, Abigail A Howell, Susanne P Pfeifer

Bacteriophages, viruses that infect bacteria, have been silently waging the largest war on Earth for millions of years. Due to their bactericidal nature, bacteriophages have the potential to act as a countermeasure against antibiotic resistant bacteria. Therefore, the expansion of bacteriophage genomic libraries is critical to the advancement of bacterial treatments. As part of the HHMI-SEA-PHAGES program, a cohort of undergraduate students from Arizona State University (ASU) characterized and annotated the genome of Phegasus, which was isolated from the host Mycobacterium smegmatis mc2155. Phegasus is a member of the temperate P1 sub-cluster of the Siphoviridae morphotype. Using DNAMaster, GeneMark, and Starterator, 78 genes were annotated; one tRNA was found via Aragorn.