SEA-PHAGES Logo

The official website of the HHMI Science Education Alliance-Phage Hunters Advancing Genomics and Evolutionary Science program.

Abstract Summary

Below is a summary of the abstract you submitted. Presenting author(s) is shown in bold.

If any changes need to be made, you can modify the abstract or change the authors.

You can also download a .docx version of this abstract.

If there are any problems, please email Dan at dar78@pitt.edu and he'll take care of them!

This abstract was last modified on March 17, 2021 at 6:08 p.m..

University of Colorado at Boulder
Corresponding Faculty Member: Christy Fillman, christy.fillman@Colorado.EDU
This abstract WILL be considered for a talk.
Gene Function Similarities and Genome Synteny Suggest Evolutionary Relationships Between Bacteriophages
Mia Fox, Harriet Lee, Christy L Fillman, Nancy A Guild

The genome of a bacteriophage contains genes that code for functional proteins which dictate everything from phage shape to phage function. We annotated Enceladus, a temperate phage belonging to the L1 cluster. This phage was discovered at the University of Colorado at Boulder and is currently being annotated at the same institution. This research attempts to understand similarities in gene function with a focus on phages that possess genes similar to those found in Enceladus. Synteny was used to understand evolutionary relationships between phage genomes. Similarity was found between the genes coding for virion structure and assembly functions in phages belonging to clusters L,M and DU. These results indicate a possible evolutionary connection between the clusters and may be the first step to determining new evolutionary connections between bacteriophages.