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dane.bowder posted in capsid maturation protease or hypothetical protein (MuF-like minor capsid protein)
Marie Fogarty posted in capsid maturation protease or hypothetical protein (MuF-like minor capsid protein)
Debbie Jacobs-Sera posted in capsid maturation protease or hypothetical protein (MuF-like minor capsid protein)
dane.bowder posted in capsid maturation protease or hypothetical protein (MuF-like minor capsid protein)
All posts created by welkin
Link to this post | posted 16 Apr, 2018 16:45 | |
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Lysin A, which is a single multi-domain protein in many Actinobacteriophages, is split at the domain boundaries encoded by two adjacent genes in cluster DN. The functions should be reported as "lysin A, whatever the domain is" to indicate that each gene does not encode the full lysin A. |
Link to this post | posted 16 Apr, 2018 16:44 | |
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Lysin A, which is a single multi-domain protein in many Actinobacteriophages, is split at the domain boundaries encoded by two adjacent genes in cluster DL. The functions should be reported as "lysin A, whatever the domain is" to indicate that each gene does not encode the full lysin A. |
Link to this post | posted 16 Apr, 2018 16:38 | |
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Cluster CX phages contain a gene that encodes a protein very similar to the integrases of the temperate phages. However, these phages do not contain any other identifiable integration machinery–immunity repressor, CRO, excise, etc; nor have we been successful in isolating lysogens. Therefore, we've decided that the "integrase" is better off labeled as "recombinase". |
Link to this post | posted 16 Apr, 2018 16:05 | |
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sounds like you are making a strong case for including the more specific one. Which way are you leaning on this? |
Link to this post | posted 16 Apr, 2018 16:04 | |
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yep. I don't really like the name "super -infection immunity protein" because there are too many different types of proteins that can accomplish that phenotype. |
Link to this post | posted 13 Apr, 2018 22:37 | |
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Lysin A is near the left end of the genome, Lysin B is two genes upstream from the tape measure protein. |
Link to this post | posted 13 Apr, 2018 22:36 | |
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Cluster DJ phages have two genes that are predicted to encode major tail proteins with good bioinformatic support. This has not been demonstrated at the bench yet, however, we are going to label both with the functional label "major tail protein". |
Link to this post | posted 13 Apr, 2018 22:35 | |
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The capsid maturation protease, scaffolding, and major capsid protein are fused in cluster DJ phages. |
Link to this post | posted 13 Apr, 2018 22:32 | |
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Lysin A, which is a single multi-domain protein in many Actinobacteriophages, is split at the domain boundaries encoded by two adjacent genes in members of cluster DI. The functions should be reported as "lysin A, whatever the domain is" to indicate that each gene does not encode the full lysin A. |
Link to this post | posted 13 Apr, 2018 22:26 | |
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We do not know where the frameshift is in the DH tail assembly chaperones. |