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The official website of the HHMI Science Education Alliance-Phage Hunters Advancing Genomics and Evolutionary Science program.

The SEA-PHAGES Program

SEA-PHAGES (Science Education Alliance-Phage Hunters Advancing Genomics and Evolutionary Science) is a two-semester, discovery-based undergraduate research course that begins with simple digging in the soil to find new viruses, but progresses through a variety of microbiology techniques and eventually to complex genome annotation and bioinformatic analyses.

The program aims to increase undergraduate interest and retention in the biological sciences through immediate immersion in authentic, valuable, yet accessible research. By finding and naming their own bacteriophages, students develop a sense of project ownership and have a ready-made personal research project at a fraction of the cost of traditional apprentice-based research programs. Some of the positive effects of the SEA-PHAGES program have been reported here.

SEA-PHAGES is jointly administered by Graham Hatfull's group at the University of Pittsburgh and the Howard Hughes Medical Institute's Science Education division.

SEA-PHAGES IN THE NEWS

  • Thumbnail for Invisible Friends

    Invisible Friends

    Story by Joel Smith; photos by Rajah Bose

    Gonzaga—The Magazine of Gonzaga University | Aug. 15, 2016

    They may have goofy names, but these students’ microscopic pets are serious science. A junior in college, Vina Tran already has a bona fide scientific discovery to her name. Go ahead and look her up on the Actino-bacteriophage Database, a compendium of biological findings maintained by the University of Pittsburgh....read more

    Related institution: Gonzaga University

  • Thumbnail for This scientific paper has 2,863 authors. How?

    This scientific paper has 2,863 authors. How?

    Danielle Wiener-Bronner

    Fusion | May 12, 2015

    The scientific journal eLife published a paper on viruses last month—specifically, the genetics of bacteriophages: viruses that infect, and replicate within, bacteria. By sequencing the genomes of individual bacteriophages, or phages, the authors were able to glean information about the genetic makeup of the viruses more broadly.... read more

  • Thumbnail for  Steele commended by Nobel Prize winner for her work

    Steele commended by Nobel Prize winner for her work

    Barbara Phillips

    Archer County News | April 21, 2016

    It is not often that a freshman in college is approached and commended for research by a Nobel Prize winner, but that is exactly what happened to Archer City graduate, London Steele, now a freshman at Baylor University....read more

    Related institution: Baylor University

  • Thumbnail for Queens University student discovers a virus strain

    Queens University student discovers a virus strain

    Reid Creager

    The Charlotte Observer | April 16, 2016

    Sydney Dishman’s new pet isn’t cute and certainly isn’t something you’d want to cuddle with. But she feels good just thinking about it. Her “pet” is named Rex16, after the Queens University of Charlotte mascot and her year of graduation. Rex16 is a bacteriophage species she discovered while completing her honors research thesis, investigating bacteriophages in local soil samples....read more

    Related institution: Queens University of Charlotte

  • Thumbnail for Students isolate potentially novel soil-dwelling viruses

    Students isolate potentially novel soil-dwelling viruses

    WPI News

    Phys.org | June 8, 2016

    After sifting through soil samples collected from across Massachusetts, then drilling down to analyze the DNA of viruses they found, a team of undergraduates at Worcester Polytechnic Institute (WPI) hit pay dirt—three potentially novel viruses.... read more

    Related institution: Worcester Polytechnic Institute

  • Thumbnail for Going viral: C of I students attend HHMI symposium

    Going viral: C of I students attend HHMI symposium

    The College of Idaho—Student News | Aug. 4, 2015

    Jetblade. The name might sound like the newest Marvel superhero to hit the big screen, but it’s actually the newest bacterial virus analyzed by College of Idaho students....read more

    Related institution: College of Idaho

  • Thumbnail for Student ‘Virus Hunters’ publish research in peer journal

    Student ‘Virus Hunters’ publish research in peer journal

    FGCU 360 | July 2, 2015

    Students and faculty involved in FGCU’s “Honors Virus Hunters” course helped produce a research paper that has been accepted for publication in eLife, a highly ranked peer-reviewed scientific journal for the biomedical and life sciences....read more

    Related institution: Florida Gulf Coast University

  • Thumbnail for WKU 2012 Goldwater Scholarship Recipient Charles Coomer

    WKU 2012 Goldwater Scholarship Recipient Charles Coomer

    innovateKY/YouTube | April 24, 2012

    Charles Coomer, a junior in the Honors College at WKU and the son of Evell and Don Coomer, has been involved in microbiological research for two years. In the lab of Dr. Rodney King, associate professor of biology, Coomer is characterizing viruses that infect bacterial cells...read more

    Related institution: Western Kentucky University

  • Thumbnail for Freshman find

    Freshman find

    Kyrie O'Connor

    Houston Chronicle | Oct. 15, 2016

    Brian Blake Maxfeldt likes science just fine, but he didn't go to college expecting to make a discovery his first year. Nevertheless, Maxfeldt, who goes by Blake and graduated from Morton Ranch High School in Katy, discovered a virus that nobody had ever seen before.read more

    Related institution: LeTourneau University

  • Thumbnail for Bio major considered dream come true for department

    Bio major considered dream come true for department

    Melanie Greenberg

    Loquitor—Cabrini College Student Media | March 5, 2011

    Surrounded by only her thoughts and glass beekers, one Cabrini student spends much of her time diligently working in the Iadarola Science Center. Katie Mageeney, senior biology major and math and chemistry minor, is anything but an average student. “Katie is definitely dedicated to her lab work,”...read more

    Related institutions: Cabrini College | Lehigh University

  • Thumbnail for Durham Tech students present research at national symposium

    Durham Tech students present research at national symposium

    Charlton Budd

    Chapelboro.com | June 27, 2016

    Two Durham Tech students were given the chance to present their research at a national symposium earlier this month. Qina Mo and Peter Said presented their research describing the isolation and characterization of two viruses that infect bacteria at the 8th annual SEA-PHAGES Symposium...read more

    Related institution: Durham Technical Community College

  • Thumbnail for One student gets to name lab discovery

    One student gets to name lab discovery

    Oscar Santiago Torres

    Eagle News | Aug. 27, 2014

    An agar plate lies still. Omnicron has destroyed the layer of bacteria inside the plate, leaving plaques or dark holes 2 mm in diameter. Omnicron is a virus replicating itself inside the plate. The discovery of this virus belongs to Tasha Baer, a Florida Gulf Coast University student from the 2013-14 Virus Hunters course....read more

    Related institution: Florida Gulf Coast University

  • Research paper with 2,863 authors expands knowledge of bacteriophages

    Science Daily | May 11, 2015

    We know that bacteriophages are viruses that infect and replicate within bacteria. We know that they are the most abundant organisms on Earth. But we don't know much about their genetic architecture....read more

    Related institution: University of Pittsburgh

  • Thumbnail for UWF Biology And Chemistry Crews Team Up To Hunt Phages

    UWF Biology And Chemistry Crews Team Up To Hunt Phages

    Bob Barrett

    wuwf 88.1 | May 12, 2015

    The University of West Florida has been chosen to pioneer a unique collaboration between its chemistry and biology departments. Let’s start off with an important definition....read more

    Related institution: University of West Florida

  • Thumbnail for A summer of sequencing

    A summer of sequencing

    Joseph McClain

    Ideation | Sept. 6, 2013

    It was the summer that the freshmen ruled the sequencer. Technically, the six William & Mary students who logged heavy lab time with a state-of-the-art Ion Torrent gene sequencer had finished their freshman year and therefore did their summer work as rising sophomores....read more

    Related institution: College of William & Mary

2017 SEA Symposium T-Shirt Design Contest

The 2017 SEA Symposium T-Shirt Design Contest is now open. Show off your creativity and enter the T-Shirt Design Contest. Your design could be chosen as the official image used on the symposium t-shirt. The winning entry and artist will also be featured on the program website. Submissions should be sent to SEA@hhmi.org by April 3, 2017.

The competition is open to SEA faculty and students. Click here to download the contest rules and guidelines

- The SEA Team

The GO Annotation Competition is upon us!

If you are annotating phage genomes in Spring, you might be interested in an exciting inter-campus Gene Ontology (GO) annotation competition devoted to phage genomes and hosted by Texas A&M University. Last year, 5 SEA-PHAGES campuses joined the competition.

GO annotations are formal statements about the function/role/location of a gene product (e.g. protein X has glucosidase activity or protein Y is part of the phage tail baseplate). As part of the competition, students have to find literature sources providing experimental evidence of a given function/role/location for a phage gene product and enter the annotation using the wiki-based interface. These annotations can be challenged and corrected by students from other campuses and instructors, and students must revise them to earn full credit. Once completed, annotations are submitted to the GO repository for everybody to see and use.

Performing GO annotations in a competitive setting is a great way to have students read, parse and distill a scientific manuscript into the elementary units of knowledge it contributes. If you are interested in participating, please contact Steve Caruso (scaruso@umbc.edu) or Ivan Erill (erill@umbc.edu) of UMBC for more information. They have abundant training material to share with you.

Sequencing Status 2016-17

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Upcoming Events

Submit Completed PITS Assessment Site Approval Letter

March 16, 2017

Identify 2016 Symposium Participant

March 16, 2017

Identify Phage Discovery Workshop Trainees

March 16, 2017

Recent Events

Orientation Webinar Option B

January 30, 2017

Forum Activity

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