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Repressor vs HTH DNA binding proteins
| Link to this post | posted 23 Aug, 2018 14:38 | |
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At this time (8-23-18 ), we felt it prudent to call the DNA binding proteins around the integrases "helix-turn-helix DNA binding proteins", even thought 2 of them are hitting Lambda's CI. (Genome used in this evaluation are Nandita and Ryan). |
| Link to this post | posted 13 May, 2021 18:50 | |
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Given that these FF cluster phage have genes in PHAM 54987 (92 members and majority calls are immunity repressor) that hit to numerous repressors such as 5FD4_B (ComR; Streptococcus, Competence, Quorum sensing, ComR, TRANSCRIPTION REGULATOR; 2.9A {Streptococcus suis (strain 05ZYH33), 6H49_A (Orf20; SaPI, Repressor, STRUCTURAL PROTEIN; HET: SO4; 1.8A {Staphylococcus aureus}) and 5D50_D (Repressor; Repressor, Anti-repressor, complex, DNA BINDING PROTEIN; 2.49A {Salmonella phage SPC32H}) an immunity repressor call is consistent with the data and the location of the genes within an immunity cluster (gp35 in Popper, gp37 in Nandita and gp37 in Ryan).
RS Pollenz
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