Hello everyone,

I'd like to present my new paper on annotation of phage genomes, entitled "A Method for Improving the Accuracy and Eciency of Bacteriophage Genome Annotation". In this paper, I present the method we use in my lab to annotate phage genome. It is based on the method we all use in SEA-PHAGES, but is a little more formal and detailed. I estimate the accuracy of the method and compare it to programs such as Glimmer and GeneMark, using the genomes of phages Lambda and Patience as test sets. It does seem that manual annotation method produces more accurate annotations, both in terms of gene calling and start codon calling, at least as far as Lambda and Patience are concerned. I think those of you interested in genome annotation will find this paper very interesting, and may find many useful things to incorporate into your annotation protocols.

Regards,
Philippos
Edited 16 Jan, 2020 01:24