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This abstract was last modified on April 21, 2015 at 3:59 p.m..

University of Colorado at Boulder
Corresponding Faculty Member: Christy Fillman, christy.fillman@Colorado.EDU
This abstract WILL be considered for a talk.
Comparing Codon Usage and tRNAs Present in a C1 Phage, Sprinklers, and a A6 Phage, ToneTone
Brianna Morgan, Whitney Stanton,

We compared the tRNAs and codon usage in two mycobacteriophages; ToneTone, a siphoviridae A6 cluster phage and Sprinklers, a C1 myoviridae phage. ToneTone contains three tRNAs while Sprinklers contains thirty tRNAs and one tmRNA. ToneTone’s tRNA’s are clustered at the beginning of the genome, while Sprinklers tRNA’s are distributed in several clusters localized mostly in the second half of the genome. Mycobacterium smegmatis, the host organism used to isolate these phages, contains 47 tRNAs. In Sprinklers’ genome we found the translational associated proteins peptidyl tRNA hydrolase type 2 and peptide chain release factor 1, which were not found in ToneTone’s genome. These tRNAs and translational factors may contribute to the fitness of these phages.